EPO Plus capsule is indicated in:
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EPO Plus Primrose is a plant native to North America. It is obtained from the seeds of the plant. It has been used medicinally in Europe since the 16th century. Clinical studies have focused on its use in the treatment of problems associated with essential fatty acid (EFA) deficiency, including premenstrual syndrome, atopic eczema, inflammation, and diabetic peripheral neuropathy. EPO Plus (EPO) is relatively high in essential fatty acids (EFAs), particularly gamma-linolenic acid (GLA,7-10%).
Improves EFA composition of plasma, erythrocytes, platelet lipids and atocopherol levels in non-diabetic persons and Type 1 diabetic patients; increase total fat and EFA contents of mother's milk; affects fatty acid composition of serum lipids and adipose tissue in men with low dihoma-gamma-linolenic acid (DGLA) levels; helps maintain normal cellular structures and in the precursor of DGLA, which is the parent of the 1-series prostanoids and as a precursor of arachidonic acid, the parent of the 2-series prostanoids.
Evening Primrose Oil supplies gamma-linolenic acid (GLA). The bioactivity of EPO is due primarily to its GLA contents. By supplying GLA, it bypasses the rate-limiting step in the metabolism of LA. After ingestion of EPO, GLA is rapidly absorbed and then converted directly to DGLA and other prostaglandin precursors. It also acts on the prostaglandin pathway.
Atopic & Allergic Dermatitis:
Benign Breast disease & Mastalgia: 1 capsule 2/3 times daily with or after a meal.
Premenstrual Syndrome (PMS): 1 Capsule 2 times daily in the morning & evening with or after a meal.
Rheumatoid arthritis: 1 Capsule daily or as directed by the registered physician.
Previously, it was not recommended for patients diagnosed with schizophrenia. However, a recently published analysis of clinical trials involving polyunsaturated fatty acids in the treatment of schizophrenia did not indicate a clear therapeutic or adverse effect of evening primrose oil supplements on schizophrenic patients.
Side effects are rare at recommended dosages. An overdose may cause loose stools and abdominal pain.
Linolenic acid, GLA, and DGLA are important components of human breast milk, so it is important to ensure that evening primrose oil can be taken while nursing. According to the World Health Organization (WHO), pregnant or lactating women should get 5% of their total daily caloric intake from EFAs.
Keep out of reach of children. Keep away from direct sunlight. Store below 25°C in a dry place.
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