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Generic Name: Mefenamic Acid 50mg/5ml
Manufacturer/Distributor: Cosmic Pharma Ltd.
✅ Description:
Indications
Mefenamic Acid is indicated for-
- Fever
- Toothache
- Headache
- Migraine
- Primary dysmenorrhoea
- Menorrhagia
- Mild to moderate pain in rheumatoid arthritis and osteoarthritis
- Traumatic pain
- Low-back pain
- Juvenile chronic arthritis in children etc.
Pharmacology
Mefenamic acid is a nonsteroidal drug that has been shown to have analgesic, anti-inflammatory, and antipyretic properties due to its dual action on prostaglandins. Prostaglandin synthetase enzymes are inhibited, and prostaglandin effects at receptor sites are antagonized.
Dosage & Administration
Adult:
- 500 mg dose should be given to adults up to three times (1.5 gm total) per day with meals. The dosage may be reduced to 1 tablet (250 mg) three times daily.
- In case of menorrhagia: 500 mg three times daily with meals and from the onset of menses and continued according to the judgment of the physician.
Children:
- 6 months to 1 year: 5 ml three times/day.
- 2-4 years: 10 ml three times/day.
- 5-8 years: 10 ml four times /day.
- 9-12 years: 15 ml four times/day.
Treatment should not be continued for more than 7 days except on the advice of a physician.
Interaction
Concomitant use of Mefenamic Acid with Aspirin is not generally suggested, as it is with other NSAIDs, due to the risk of increased side effects.
In people on warfarin, mefenamic acid can suppress platelet aggregation and lengthen the prothrombin time.
Contraindications
It's not recommended for people who have a history of Mefenamic Acid hypersensitivity. Patients with a peptic ulcer, inflammatory bowel disease, or hepatic or renal impairment should not use it. It's also not recommended for people who have experienced bronchospasm, skin rashes, or other side effects from aspirin or other NSAIDs.
Side Effects
Abdominal discomfort, constipation, diarrhea, dyspepsia, flatulence, nausea, Gl ulcers, vomiting, dizziness, altered renal function, pruritus, and rashes are the most commonly reported unpleasant effects, which affect about 1-10% of people.
Pregnancy & Lactation
Mefenamic acid's safety in terms of reproductive capacity and pregnancy has yet to be determined. As a result, mefenamic acid should only be taken in women of reproductive age and during pregnancy if the possible benefits are predicted to outweigh the risks. Mefenamic acid may be found in trace amounts in breast milk and passed on to the nursing newborn. Because of the effects of this family of medications on the cardiovascular system of the infant, Mefenamic acid should not be used by the nursing mother.
Precautions & Warnings
In allergic illnesses, notably asthma, it should be used with caution. Diarrhea, rashes, cholestatic jaundice, thrombocytopenia, and hemolytic anemia should all be treated with caution.
Storage Conditions
Keep away from light, and store in a cool and dry place. Keep out of reach of children.
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