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P-Don 10mg (10pcs)
Generic Name: Domperidone Maleate 10mg
Manufacturer/Distributor: Pharmadesh Laboratories Ltd.
✅ Description:
Indications
A prescription drug called P-Don is used to treat nausea, vomiting, and indigestion. It enhances food movement in the stomach, which helps with digestion, and blocks the brain chemical that causes nausea or vomiting. P-Don is taken in the prescribed dose and time frame before meals.
Pharmacology
P-Don is a dopamine antagonist that principally blocks the dopamine receptors located in the ChemoreceptorTrigger Zone (CTZ) and stomach.
Dosage & Administration
P-Don should be taken 15-30 minutes before meals and, if necessary, before retiring.
Interaction
may counteract bromocriptine's hyperprolactinaemic effects. antimuscarinics and opioid analgesics may counteract the prokinetic effect. Possible Fatal: Strong CYP3A4 inhibitors, such as ritonavir, erythromycin, or ketoconazole, may raise serum domperidone levels, raising the risk of QT prolongation in the process.
Contraindications
P-Don is contraindicated to patients having known hypersensitivity to this drug and in the case of neonates.
Side Effects
P-Don may produce hyperprolactinemia (1.3%). This may result in
- Drowsiness
- Extrapyramidal reactions
- Decreased libido
- Skin rash,
- Itch.
- Lassitude
- Galactorrhea,
- Breast enlargement, Soreness, and
- Reduced libido.
Pregnancy & Lactation
The safety of P-Don has not been proven and it is therefore not recommended during pregnancy.
Precautions & Warnings
- P-Don is highly metabolized in the liver, it should be used with caution in patients with hepatic impairment.
- Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.
- Do not take it for longer than 7 days without consulting your doctor.
Storage Conditions
Store below 30°C, Protected from light & moisture.
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