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Dialon is used to lower blood glucose levels in patients with Type II diabetes mellitus (NIDDM) when diet and exercise alone are insufficient. It can be used:
- Alone as an adjunct to diet and exercise.
- In combination with metformin if either medication alone does not provide adequate glycaemic control.
- Alongside insulin therapy when blood glucose cannot be controlled by diet, exercise, and an oral hypoglycaemic agent alone.
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✅ Description:
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ How does Dialon (Glimepiride) work?
Glimepiride, the active ingredient in Dialon, is a sulfonylurea that helps reduce blood glucose levels by:
- Stimulating insulin release from pancreatic beta cells.
- Increasing the sensitivity of beta cells to glucose.
- Reducing basal hepatic glucose production.
- Increasing glucose uptake in peripheral tissues.
✔️ What is the recommended dosage of Dialon?
The dosage is determined based on individual patient needs and blood glucose monitoring:
- Initial dose: 1 mg once daily before breakfast or the first main meal.
- Dose titration: Can be increased gradually at 1-2 week intervals (1 mg → 2 mg → 3 mg → 4 mg → 6 mg daily).
- Well-controlled diabetes: Usually requires 1-4 mg per day.
- Changing from other oral antidiabetics: Start with 1 mg daily, adjusting based on response.
✔️ How should Dialon be taken?
Dialon should be taken orally with a sufficient amount of liquid. The tablet should be consumed before a substantial meal to prevent hypoglycemia.
✔️ Common side effects include:
- Hypoglycaemia (low blood sugar)
- Temporary visual impairment
- Nausea, vomiting, diarrhea, abdominal pain
- Allergic reactions such as urticaria
- Drop in blood pressure
✔️ Dialon is not suitable for:
- Type I diabetes mellitus (insulin-dependent diabetes)
- Diabetic ketoacidosis or diabetic coma
- Patients with severe liver or kidney dysfunction
- Those with hypersensitivity to Glimepiride, sulfonylureas, or sulfonamides
✔️ What should I do in case of an overdose?
An overdose can lead to severe hypoglycemia.
- Mild symptoms: Consume glucose or sugar immediately and adjust the dosage or meal patterns.
- Severe reactions (coma, seizures): Seek emergency medical help. Treatment includes rapid intravenous glucose administration followed by continuous glucose infusion.
✔️ What medications can interact with Dialon?
Certain medications can either enhance or weaken the hypoglycaemic effect of Dialon:
- Increase hypoglycaemia risk: ACE inhibitors, anabolic steroids, salicylates, sulfonamide antibiotics, MAO inhibitors, fluconazole, quinolones.
- Reduce hypoglycaemic effect: Corticosteroids, diuretics, thyroid hormones, phenothiazines, rifampicin.
- Beta-blockers and clonidine: May mask hypoglycaemic symptoms.
- Alcohol: Can unpredictably potentiate or weaken Dialon’s effects.
✔️ Can Dialon be taken during pregnancy and breastfeeding?
No, Dialon should not be taken during pregnancy. Patients planning a pregnancy should switch to insulin. Dialon must also not be used while breastfeeding, as it may harm the child.
✔️ What precautions should be taken while using Dialon?
- Regular monitoring of blood glucose levels is necessary.
- Hypoglycaemia risk is higher in the initial treatment weeks.
- Avoid skipping meals after taking Dialon to prevent hypoglycemia.
- Adjust dosage in case of significant lifestyle or weight changes.
✔️ How should Dialon be stored?
- Store below 30°C.
- Keep away from direct light and moisture.
- Keep out of reach of children.
Disclaimer:
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information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
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