Losucon 3mg Tablet

✔️ Uses of Losucon 3mg Tablet

• Treats Type II Diabetes Mellitus

✔️ How does Losucon 3mg Tablet work?

In Type 2 diabetes, the pancreas manufactures a hormone called insulin, which aids in transferring sugar (glucose) from the bloodstream into cells, where it serves as an energy source. However, in this condition, the body either produces insufficient insulin or fails to utilize it effectively. Consequently, glucose remains in the bloodstream instead of entering cells.

Glimepiride operates by augmenting the release of insulin from the pancreas. This increased insulin amount works to decrease blood sugar levels by facilitating the uptake of glucose into cells. As a result, Glimepiride helps address the issue of elevated blood sugar commonly observed in Type 2 diabetes.

✔️ Side Effects of Losucon 3mg Tablet

• Allergic reactions
• Headache
• Nausea
• Blood pressure drop
• Shock
• Abnormal liver function
• Including skin and eye yellowing (jaundice)
• Bile flow issues (cholestasis)
• Liver inflammation (hepatitis) or failure of the liver

✔️ Quick Suggestions:

• Losucon 3mg Tablet is a medication designed to combat diabetes. Specifically intended for managing type 2 diabetes mellitus, its function involves reducing elevated blood sugar levels. The active component is glimepiride.
• For optimal outcomes, it's advisable to adhere to a consistent daily schedule for taking the tablet. This practice ensures a steady presence of the medication in your system.
• Incorporating certain lifestyle changes alongside Losucon 3mg Tablet is vital. Engaging in regular exercise, walking, refraining from smoking, and moderating alcohol consumption contributes to enhanced results.
• Adopting a balanced diet, rich in fruits and vegetables, is key to effectively controlling blood sugar levels. Keeping track of your blood sugar levels on a routine basis is also recommended.
• Prior to initiating Losucon 3mg Tablet, it's imperative to inform your doctor about pregnancy, plans for pregnancy, breastfeeding, and provide a comprehensive medical history.
• Possible side effects include weight gain, low blood sugar, increased appetite, dizziness, and nausea/vomiting. If these effects persist or are bothersome, consulting your doctor is advisable.
• In instances where drowsiness, unconsciousness, or confusion ensue after using the tablet, refraining from driving or operating heavy machinery is crucial.
• Individuals with kidney or liver ailments should have a dialogue with their doctor before starting the medication.
• If a dose of Losucon 3mg Tablet is missed, it's best to take it as soon as remembered. If the next dose is impending, it's advised to skip the missed dose and administer the subsequent one at the usual time.

✔️ Indication of Losucon 3mg Tablet

Losucon 3mg Tablet is used in the treatment of type 2 diabetes mellitus when diet and exercise fail to control your blood sugar levels.

✔️ Pharmacology

Glimepiride: Sulfonylurea anti-diabetic agent.

• Effectively lowers blood glucose levels.
• Primary action involves enhancing insulin release from active pancreatic beta cells.
• Collaborates with glucose to heighten beta cell responsiveness to natural glucose triggers, prompting insulin secretion.
• Potential extrapancreatic impacts include decreased hepatic glucose production, improved peripheral tissue insulin sensitivity, and enhanced glucose absorption.
• A solitary dose of Glimepiride yields a 24-hour hypoglycemic impact in non-fasting diabetic individuals.

✔️ Dosage & Administration of Losucon 3mg Tablet

Adult Dose:

• Type 2 diabetes mellitus.
• Start with 1-2 mg daily.
• Incremental increases of 1-2 mg at 1-2 week intervals.
• Maintenance: 4 mg daily.
• Maximum: 6 mg daily.
• Elderly: Begin with 1 mg once daily.
• Severe hepatic impairment: Avoid use.

Child Dose:

• Safety and efficacy not established.

Renal Dose:

• Renal impairment: 1 mg PO once daily; adjust based on fasting blood glucose levels.
• Severe renal impairment: Avoid use.

Missed Dose:

• If you miss a dose, take it once recalled.
• If the next dose time is near, skip the missed dose.
• Avoid doubling up on doses.

Overdose:

• Excessive consumption may lead to symptoms such as dizziness, confusion, increased heartbeat, tremors, sweating, etc.
• Seek immediate medical help for guidance.

Administration:

• Take with food, preferably right before or during breakfast, or the first main meal.
• Avoid skipping meals.

✔️ Interaction

Interactions with Other Medicines:

• Inform your doctor about all medications, herbal preparations, and supplements to prevent interactions with Losucon 3mg Tablet.
• Certain medications, when taken with Losucon 3mg Tablet, can lead to a significant drop in blood glucose levels: Fluconazole, Aspirin, Metformin, Insulin, Warfarin, Ramipril, Lisinopril, Allopurinol.
• Some medicines might affect Losucon 3mg Tablet's effectiveness and cause elevated blood glucose: Oestrogens, Progestogens, Diuretics, Levothyroxine, Rifampicin, Glucocorticoids, and Chlorpromazine.
• Beta-blockers (e.g. Propranolol) can excessively lower blood sugar and mask symptoms of low blood sugar.

Interactions with Food:

• Follow the diabetic diet recommended by your doctor or dietician.
• Losucon 3mg Tablet's efficacy is enhanced with proper diet and exercise.
• Exercise reduces insulin resistance and complements the medication's effects.

✔️ Contraindications

Glimepiride Contraindications:

• Not suitable for insulin-dependent (Type I) diabetes mellitus.
• Avoid in cases of diabetic ketoacidosis or diabetic coma.
• Contraindicated for individuals hypersensitive to glimepiride, other sulfonylureas, or sulfonamides.
• Avoid significant hepatic dysfunction.
• Not recommended for severe renal function impairment or dialysis patients.

✔️ Pregnancy & Lactation

Pregnancy and Breastfeeding Considerations:

• Glimepiride is not safe during pregnancy.
• Insulin is the preferred choice for pregnant individuals.
• Those planning pregnancy should inform their doctor and switch to insulin.
• Glimepiride consumption combined with breastfeeding might harm the infant.
• Nursing mothers should abstain from using Glimepiride.
• Transitioning or ceasing breastfeeding is advised.

✔️ Precautions & Warnings

• Inform your doctor if recovering from an injury, undergoing surgery, experiencing fever, infections, or stress.
• Adjustments in care might be necessary during these times.
• Serious kidney/liver disease, pregnancy, breastfeeding - consult your doctor before using Glimepiride.
• Avoid Glimepiride if allergic to sulfa drugs, glimepiride, or other antidiabetic medications.
• Individuals with glucose 6-phosphate dehydrogenase (G6PD) deficiency should not take Glimepiride.
• Heart disease patients should consult a doctor due to potential impact on existing conditions.
• Avoid concurrent use of Glimepiride with oral contraceptives, as it might elevate blood sugar levels.
• Conversely, combining Glimepiride with pain relievers like aspirin or ibuprofen may lower blood sugar.

✔️ Storage Conditions

Store in a cool and dry place away from sunlight. Try to keep it out of the reach of children and pets.