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Mecolagin - IM/IV 500 Injection (5pcs)
Type: Injection
Pack Size: 5 Pcs
Generic Name: Mecobalamin 500mcg/ml
Manufacturer: Incepta Pharmaceuticals Ltd.
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✅ Description:
Indications
Peripheral Neuropathies
Diabetic Neuropathy
Verteberal Syndrome
Nerve Compression Syndrome
Multiple sclerosis
Amyotrophic lateral sclerosis
Parkinson’s disease
Alzheimer’s disease
Diabetic retinopathy
Entrapment neuropathy
Drug induced neuropathy
Megaloblastic anemia due to Vitamin B12 deficiency
Pharmacology
Mecobalamin is the neurologically active form of vitamin B12, which is found in the body as a water-soluble vitamin. It's a cofactor in the enzyme methionine synthase, which helps methionine regenerate from homocysteine by transferring methyl groups. It boosts erythrocyte production in anemia by boosting nucleic acid synthesis in the bone marrow as well as erythrocyte maturation and division.
Dosage & Administration
Tablet: The usual adult dosage is 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms.
Injection:
Peripheral neuropathies: The usual adult dosage is 500 mcg Mecobalamin administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms.
Megaloblastic anemia: The usual adult dosage is 500 mcg Mecobalamin administered intramuscularly or intravenously three times a week. After about two months of administration, dosage should be changed to one ampoule equivalent to 500 mcg of Mecobalamin every one to three months as maintenance therapy.
Interaction
Neomycin, aminosalicylic acid, H2-blockers, and colchicine all reduced GI tract absorption. Oral contraceptives lower serum concentrations. Parenteral chloramphenicol has less of an effect on anemia.
Contraindications
Hypersensitivity to any of the product's ingredients.
Side Effects
Mecobalamin is generally well tolerated. However, following the delivery of Mecobalamin, some adverse effects such as GI discomfort (including anorexia, nausea, or diarrhea) and rash may occur.
Pregnancy & Lactation
It is not advised to use during pregnancy or nursing.
Precautions & Warnings
If there is no response to the treatment after a particular period of time, it should not be used for months.
Storage Conditions
Store at room temperature if used orally. Moisture and light should be avoided.
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