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Fexo 180mg 10pcs
Generic Name: Fexofenadine Hydrochloride 180mg
Manufacturer: Square Pharmaceuticals Ltd.
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✅ Description:
Indications
Fexo 180 is a member of the class of drugs known as antihistamines. It is employed in the treatment of a number of allergic diseases, including hay fever, conjunctivitis, and some skin reactions like eczema, hives, and reactions to bites and stings. Additionally, it stops itching, sneezing, runny nose, and watery eyes.
Pharmacology
An antihistamine with specific peripheral H,-receptor antagonist action is fexofenadine hydrochloride. After oral administration, fexofenadine is rapidly absorbed, and peak plasma concentrations are attained in 2–3 hours. About 60 to 100of it is bound to plasma proteins. Only 0.5 to 1.57% of the total dosages are biotransformed by the cytochrome P456 system in the liver, with the majority of the remaining 50% being metabolized by the intestinal mucosa. The elimination half-life of 14 hours has been recorded, while patients with renal impairment may experience a longer half-life. Only 100% being is excreted in the urine; the majority is excreted in the feces. The blood-brain barrier does not appear to be crossed by fexofenadine.
Dosage & Administration
Seasonal Allergic Rhinitis-
Adults and children 12 years and older:
- Tablet: 60 mg twice daily or 120 mg once daily or 180 mg once daily
- In case of impaired renal function: 60 mg once daily
- Children from 6 to 11 years:
- Tablet: 30 mg twice daily or 60 mg once daily
- In case of impaired renal function: 30 mg once daily
- Children from 2 to 11 years
- Suspension: 30 mg or 5 ml twice daily
- In case of impaired renal function: 30 mg or 5 ml once daily
Chronic Idiopathic Urticaria-
Adults and children 12 years and older:
- Tablet: 60 mg twice daily or 120 mg once daily or 180 mg once daily
- In case of impaired renal function: 60 mg once daily
Children from 6 to 11 years:
- Tablet: 30 mg twice daily or 60 mg once daily
- In case of impaired renal function: 30 mg once daily
Children from 6 months to less than 2 years:
- Suspension: 15 mg or 2.5 ml (1/2 tsp) twice daily
- In case of impaired renal function: 15 mg or 2.5 ml (1/2 tsp) once daily
Children from 2 to 11 years:
- Suspension: 30 mg or 5 ml (1 tsp) twice daily
- In case of impaired renal function: 30 mg or 5 ml (1 tsp) once daily
Interaction
Plasma concentrations ofFexofenadinehavgbeen increased when given with Erythromycin or Ketoconazole. Antacid containing Aluminium and Magnesium Hydroxide reduces the absorption of Fexofenadine. Fruit juices including grapefruit may reduce the bioavailability of Fexofenadine and use together should be avoided.
Contraindications
Fexofenadine is contraindicated in patients with known hypersensitivity to any of the ingredients.
Side Effects
Headache, tiredness, sleepiness, nausea, dry mouth, and gastrointestinal problems are all common adverse effects.
Pregnancy & Lactation
Fexofenadine Hydrochloride is classified as pregnancy category C by the US Food and Drug Administration. So, unless the potential advantages to the other outweigh the potential dangers to the fetus, Fexofenadine Hydrochloride should be avoided during pregnancy and breastfeeding.
Precautions & Warnings
Patients who are old or have impaired renal function should be treated with caution.
Storage Conditions
Tablet: Store below 30oC, protect from light & moisture. Suspension: Store below 30'C. Protect from light and moisture, Keep out of children's reach.
Relevant Products / প্রাসঙ্গিক পণ্য
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