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Minomal R 350mg Tablet
Minomal R 350mg Tablet is used for the prevention and treatment of asthma and COPD by relaxing the bronchial muscles to ease breathing.
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✅ Description:
Minomal R 350mg Tablet is indicated for the treatment and prevention of bronchospasm associated with asthma, emphysema, and chronic bronchitis. It is also used for treating adult cardiac asthma, left ventricular asthma, and congestive heart failure.
Minomal R 350mg Tablet contains aminophylline, a combination of theophylline and ethylenediamine. Theophylline relaxes bronchial smooth muscles by increasing intracellular cAMP levels through inhibiting phosphodiesterase, antagonizing adenosine receptors, antagonizing prostaglandins, and affecting intracellular calcium.
Use caution in patients with peptic ulcers, hyperthyroidism, high blood pressure, arrhythmias, cardiovascular diseases, or epilepsy, as these conditions may worsen. Caution is also advised in patients with heart failure, liver dysfunction, chronic alcoholism, acute febrile illness, newborns, and the elderly, as these conditions may reduce the clearance rate of theophylline, leading to elevated serum concentrations.
Safety Advices
Alcohol
UNSAFE
Use caution when consuming alcohol with Minomal R. Consult your doctor for advice.
Breastfeeding
CONSULT YOUR DOCTOR
Minomal R may be unsafe during pregnancy due to limited human studies and harmful effects observed in animal studies. The doctor will weigh the benefits versus potential risks before prescribing.
Breastfeeding
SAFE IF PRESCRIBED
Human studies suggest the drug does not pass into breast milk in significant amounts and is not harmful to the baby.
Driving
SAFE
Minomal R does not usually affect your ability to drive.
- Kidney Disease: Use with caution.
- Liver Disease:
Kidney
CAUTION
Dose adjustment may be necessary; consult your doctor.
Liver
CAUTION
Use with caution. Dose adjustment may be necessary; consult your doctor.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Uses of Minomal R 350mg Tablet
- Asthma
- Chronic obstructive pulmonary disease (COPD)
✔️ Side Effects of Minomal R 350mg Tablet
Common side effects include stomach irritation, nausea, vomiting, diarrhea, hematemesis, epigastric pain, and tremor. High doses can lead to ventricular arrhythmias or seizures as initial signs of intoxication. Other side effects may include headaches, irritability, insomnia, seizures, convulsions, hyperexcitability, palpitations, tachycardia, hypotension, circulatory failure, ventricular arrhythmia, flushing, proteinuria, diuresis, and hematuria. Inappropriate ADH syndrome can also occur.
✔️ How does Minomal R 350mg Tablet work?
Minomal R is a bronchodilator. It works by relaxing the muscles of the airways, widening them, and making breathing easier.
✔️ Quick Suggestions:
- Take at the same time each day, preferably in the evening after food.
- Does not work immediately; always keep a fast-acting (rescue) inhaler for emergencies.
- Regular blood tests may be needed to monitor potassium levels and drug concentration.
- Notify your doctor if you have a history of kidney, liver, or heart disease, or a smoking history.
- Do not discontinue use without consulting your doctor, even if you feel better.
✔️ Oral Dosage
- Chronic bronchospasm:
- Adults: Initially, 225-450 mg twice daily, increased if necessary.
- Children >3 years: Modified-release hydrate, 12 mg/kg daily increased to 24 mg/kg daily in two divided doses after 1 week.
✔️ Administration Tips:
- Swallow the tablet whole, do not chew or crush it.
- Take on an empty stomach, at least 1 hour before or 2 hours after meals.
✔️ Interaction
- Clearance of Minomal R is reduced by drugs such as allopurinol, antiarrhythmics, cimetidine, disulfiram, fluvoxamine, interferon-alpha, macrolide antibiotics, quinolones, oral contraceptives, thiabendazole, and viloxazine.
- Clearance is increased by phenytoin, anticonvulsants, ritonavir, rifampicin, and cigarette smoking.
- Increased risk of cardiac arrhythmias with sympathomimetics and halothane.
- Increased risk of convulsion with quinolones and ketamine.
✔️ Contraindications
Minomal R 350mg Tablet should not be used in patients who are allergic to xanthine or ethylenediamine. It is contraindicated in patients with active peptic ulcers due to its potential to increase the volume and acidity of gastric secretions.
✔️ Pregnancy & Lactation
The use of Minomal R Tablet in pregnant women must be balanced with the risks of uncontrolled diseases. Consult your doctor for advice specific to your condition.
✔️ Precautions & Warnings
- Patients with peptic ulcer, hyperthyroidism, high blood pressure, arrhythmia, cardiovascular diseases, or epilepsy should use Minomal R 350mg Tabletwith caution.
- Caution is also advised for patients with heart failure, liver dysfunction, chronic alcoholism, acute febrile illness, newborns, and the elderly, as theophylline clearance may be reduced in these cases.
✔️ Storage Conditions:
Store in a cool and dry place away from sunlight
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
