Xylo Plus Nasal Spray

Indications

This Nasal Spray is used to prevent and treat allergic rhinitis (such as hay fever and perennial rhinitis) that is accompanied by nasal congestion.

Pharmacology

Xylometazoline Alpha-adrenergic sympathomimetic agents include chloride. Nasal congestion is relieved by the vasoconstriction it causes. Cold sufferers can now breathe more easily through their noses.

The nasal mucosa frequently has a local effect from sodium cromoglicate. Following antigen-antibody union, it prevents sensitized mast cells from producing type-l allergic response mediators such as histamine and slow-responding substance of anaphylaxis (SRS-A). The drug doesn't stop IgE from attaching to the specific antigen; instead, it stops the chemicals that are released as a result of this reaction (such as histamine and SRS-A). The drug also inhibits Type-III (late allergic, Arthers) responses, but to a lower level.

Dosage 

Adults (including the elderly) and children: One spray on each nostril four times daily.

Administration

How to use the Nasal Spray-

• Shake the bottle gently and remove the dust cover.
• Hold the spray with your forefinger and middle finger on either side of the nozzle and your thumb underneath the bottle. Press down until a fine spray appears. If using it for the first time or if you have not used it for a week or more, press the nasal applicator several times until a fine moist comes out from the container.
• Gently blow the nose to clear the nostrils.
• Close one nostril and carefully insert the nasal applicator into the open nostril. Tilt your head forward slightly and keep the spray upright. Breathe in through your nose and while breathing in, press the white-collar nasal applicator firmly down once to release a spray.
• Breathe out through your mouth.
• Repeat the above steps in the same/another nostril for consecutive doses.

Cleaning: The nasal spray should be cleaned at least once a week. The procedures are as follows-

• Remove the dust cover.
• Gently pull off the nasal applicator.
• Wash the applicator and dust cover in warm water.
• Shake off the excess water and leave it to dry in a normal place. Avoid applying additional heat.
• Gently push the applicator back on the top of the bottle and re-fix the dust cover.

Interaction

No information was provided.

Contraindications

In individuals who have a known allergy to any of the preparation's components, this medication is contraindicated.

Side Effects

There have been no significant adverse effects recorded. The nasal mucosa may be irritated on occasion on the first day of usage. Wheezing and chest tightness have been recorded in rare situations while using Sodium Cromoglicate solutions alone. Because this formulation contains a lesser dosage of Xylometazoline, it produces minor side effects such as nasal irritation, dryness of the nose, sneezing, headache, sleeplessness, sleepiness, and palpitations.

Pregnancy & Lactation

Caution should be used during pregnancy, as with other medications, especially during the first trimester.

Precautions & Warnings

Decongestants, in general, can cause rebound congestion or drug-induced rhinitis if used or abused for an extended period of time.

Storage Conditions

Keep below 30°C and away from light and moisture. Keep out of children's reach