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Micosone 2%+1% Ointment 10g Tube
Hydrocortisone 1% + Miconazole Nitrate 2% is used topically for treating inflamed skin conditions (dermatoses) where both infection and inflammation are present. These include:
- Eczema and dermatitis (moist or dry), such as atopic eczema, contact dermatitis (irritant or allergic), and seborrheic eczema (including cases associated with acne)
- Intertrigo and other intertriginous conditions, including inflammation in skin folds, perianal, and genital dermatitis
Miconazole is effective against dermatophytes, pathogenic yeasts like Candida spp., and many Gram-positive bacteria, including Staphylococcus and Streptococcus strains.
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✅ Description:
Miconazole belongs to the imidazole class of antifungal agents and works by inhibiting ergosterol synthesis, which disrupts fungal cell membrane integrity, leading to cell death. It is active against a range of fungi, including Candida, Aspergillus, Cryptococcus neoformans, and Pseudallescheria boydii, along with certain Gram-positive bacteria.
Hydrocortisone is a synthetic form of the naturally occurring glucocorticoid. It exerts anti-inflammatory, antipruritic, antifungal, and vasoconstrictive effects. When applied topically, it penetrates skin cells and blocks the release of substances responsible for inflammation, thus reducing swelling, redness, and itching.
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✔️ Dosage & Administration
Apply a thin layer of the cream to the affected area 2 to 4 times daily for 1 to 2 weeks, gently massaging it into the skin until fully absorbed. Continue treatment for at least one week after all symptoms have cleared to prevent recurrence. The dosage is the same for adults and children.
✔️ Drug Interactions
Amphotericin B may reduce the effectiveness of miconazole when used simultaneously.
✔️ Contraindications
Do not use in individuals allergic to miconazole, hydrocortisone, or any components of the formulation.
Should not be used during pregnancy or lactation without consulting a healthcare provider.
✔️ Side Effects
- Local irritation or sensitivity may rarely occur.
- Prolonged use can suppress natural hormone production from the adrenal glands.
✔️ Pregnancy & Lactation
High doses of corticosteroids in animal studies have shown potential fetal developmental risks. Therefore, topical corticosteroids should be used cautiously and not extensively during pregnancy.
✔️ Precautions & Warnings
- To be used only with a valid prescription from a registered medical professional.
- Keep out of reach of children.
- Special caution is advised when using in children or elderly patients, particularly during long-term treatment.
✔️ Storage Conditions
Store below 30°C, away from direct light and moisture. Keep out of children’s reach.
