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Ropitor 40 is a cholesterol-lowering statin that blocks the enzyme HMG-CoA reductase, which is essential for cholesterol production in the liver. It reduces LDL (bad cholesterol) and triglycerides while increasing HDL (good cholesterol).
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✅ Description:
Rosuvastatin
- High cholesterol (Hyperlipidemia)
- Mixed dyslipidemia
- Familial hypercholesterolemia (heterozygous and homozygous)
- Prevention of cardiovascular events (heart attack, stroke)
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Dosage & Administration
Adults:
- Initial dose: 5–10 mg once daily
- Maintenance: Up to 20 mg daily; Maximum: 40 mg/day
Administration: May be taken with or without food, preferably at the same time daily
Children (10+ years):
- Start with 5 mg once daily; may increase to max 20 mg/day
Renal Impairment:
- For CrCl <30 mL/min: Max 10 mg/day
- Not recommended in severe renal failure, not on dialysis
✔️ Drug Interactions
- May increase the effects of warfarin, oral contraceptives
- Interacts with itraconazole, HIV protease inhibitors, gemfibrozil, cyclosporin – increased risk of rhabdomyolysis
- Reduced effect with antacids, erythromycin
✔️ Side Effects
- Muscle pain (myalgia), fatigue, headache
- Abdominal pain, nausea, constipation
- Dizziness, increased liver enzymes
- Flu-like symptoms, pharyngitis
- Myopathy, rhabdomyolysis (potentially fatal)
- Jaundice, elevated creatine kinase
✔️ Contraindications
- Active liver disease
- Severe renal impairment
- Pregnancy or breastfeeding
- Unexplained persistent elevation of liver enzymes
- Hypersensitivity to rosuvastatin
✔️ Precautions & Monitoring
- Monitor liver function and creatine kinase (CK)
- Use cautiously in patients with renal impairment, hypothyroidism, alcoholism, or chronic liver disease
- Discontinue if signs of muscle toxicity or significant enzyme elevation occur
✔️ Pregnancy & Lactation
Contraindicated. Statins can harm fetal development and may pass into breast milk. Use effective contraception while on therapy.
✔️ Storage
Store in a cool, dry place, away from light and moisture. Keep out of reach of children.
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here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
