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Inospiron 100mg 10pcs
Tablet, Generic Name: Spironolactone BP, Manufacturer: Incepta Pharmaceuticals Ltd.
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Safety Advices
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Uses of
✔️ How does
✔️ Side Effects of
- Gynecomastia.
- Gastrointestinal issues.
- Sleepiness, lethargy.
- Headache.
- Urticaria.
- Mental disorientation.
- Impotence.
- Irregular menstruation or amenorrhea.
- Post-menopausal hemorrhage.
✔️ Quick Suggestions:
✔️ Indications:
- Treatment of congestive heart failure.
- Management of hepatic cirrhosis with ascites and edema.
- Nephrotic syndrome.
- Primary hyperaldosteronism.
- Essential hypertension.
- Hypokalemia.
✔️ Pharmacology
- Selective aldosterone antagonist.
- Acts by competing for receptor binding at aldosterone-dependent sodium-potassium exchange site.
- Increases sodium and water excretion while retaining potassium.
- Functions as both a diuretic and antihypertensive agent.
✔️ Dosage & Administration:
- Edema in adults: Initial daily dosage of 100 mg, ranging from 25 to 200 mg daily.
- Primary hyperaldosteronism: 100 to 400 mg daily.
- Essential hypertension: Initial daily dosage of 50 to 100 mg.
- Hypokalemia: 25 mg to 100 mg daily.
✔️ Interaction
- Concurrent use of ACE inhibitors may lead to severe hyperkalemia.
- Interaction with alcohol, barbiturates, narcotics, corticosteroids, ACTH, lithium, and digoxin.
✔️ Contraindications
- Acute renal insufficiency.
- Severe impairment of renal function.
- Anuria.
- Hyperkalemia.
- Spironolactone sensitivity.
✔️ Pregnancy & Lactation
- Not recommended during pregnancy.
- Canrenone, an active metabolite, is found in breast milk during lactation.
✔️ Precautions & Warnings
- Monitor for signs of fluid or electrolyte imbalance.
- Risk of hyperkalemia in individuals with impaired renal function or excessive potassium intake.
✔️ Storage Conditions
- Store in a cold, dry, and light-protected location.
- Keep out of children's reach.
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