Cefaclav Powder For Suspension | 70ml Bottle
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Cefaclav Powder For Suspension | 70ml

Generic: Cefuroxime Axetil + Clavulanic Acid

Type: Suspension

Pack Size: 70ml

Cefaclav is an antibiotic medicine designed to treat infections caused by bacteria sensitive to its active ingredients—Cefuroxime and Clavulanic Acid. Cefuroxime, a second-generation cephalosporin, disrupts bacterial cell wall synthesis, while Clavulanic Acid inhibits beta-lactamase enzymes, enhancing the antibiotic's effectiveness against resistant strains.

✅ Take with food to prevent stomach upset
✅ Complete the full course, even if symptoms improve early
✅ Do not share leftover medicine
✅ Stop and consult your doctor if rash, swelling, or breathing trouble occurs
✅ Consider probiotics if you experience diarrhea
✅ Always follow your doctor's instructions

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✅ Description:

Cefaclav is used for treating various bacterial infections, including:

  1. Pharyngitis/Tonsillitis: Caused by Streptococcus pyogenes
  2. Acute Otitis Media: Due to Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, or Streptococcus pyogenes
  3. Acute Maxillary Sinusitis: Caused by non-beta-lactamase-producing S. pneumoniae and H. influenzae
  4. Lower Respiratory Tract Infections (e.g., Pneumonia): Caused by S. pneumoniae, H. influenzae, Klebsiella spp., Staphylococcus aureus, S. pyogenes, and E. coli
  5. Exacerbations of Chronic Bronchitis & Acute Bronchitis: Due to S. pneumoniae, H. influenzae, or H. parainfluenzae
  6. Skin and Soft Tissue Infections: From S. aureus or S. pyogenes
  7. Urinary Tract Infections: Caused by E. coli or Klebsiella pneumoniae
  8. Bone and Joint Infections: Due to S. aureus
  9. Gonorrhoea: Uncomplicated infections from Neisseria gonorrhoeae
  10. Lyme Disease (early stage): Borrelia burgdorferi
  11. Septicemia & Meningitis: Due to organisms like S. aureus, S. pneumoniae, E. coli, H. influenzae, Klebsiella spp., and N. meningitidis
  12. Switch Therapy: From IV to oral route
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✔️ Pharmacology

Cefuroxime is bactericidal and disrupts bacterial cell wall formation.

Clavulanic Acid binds to and inhibits beta-lactamase enzymes, protecting Cefuroxime from enzymatic degradation.

✔️ Dosage & Administration

Adults & Adolescents (13+ years):

  • Pharyngitis/Tonsillitis: 250 mg twice daily for 5–10 days
  • Maxillary Sinusitis: 250 mg twice daily for 10 days
  • Bronchitis: 250–500 mg twice daily for 5–10 days
  • Skin Infections/UTIs: 250–500 mg twice daily for 7–10 days
  • Gonorrhoea: Single dose of 1000 mg
  • Pneumonia: 250–500 mg twice daily for 5–10 days
  • Typhoid Fever: 500 mg twice daily for 10–14 days
  • Lyme Disease: 500 mg twice daily for 20 days

Children (3 months–12 years):

Pharyngitis/Tonsillitis: 20 mg/kg/day divided twice daily for 5–10 days

Otitis Media, Sinusitis, Impetigo: 30 mg/kg/day divided twice daily for 10 days

Note: Can be taken with or without food.

✔️ Use During Pregnancy & Lactation
  • Avoid in the first trimester unless necessary.
  • Safe in later pregnancy for treating infections.
  • Trace amounts may be present in breast milk; monitor infant for allergic responses.
✔️ Side Effects

Generally well-tolerated. Possible side effects include:

  • Gastrointestinal issues: nausea, vomiting, diarrhea, abdominal pain
  • Rare reactions: renal dysfunction, anaphylaxis, angioedema, rashes, or serum sickness
  • Long-term use may cause overgrowth of non-sensitive organisms
✔️ Drug Interactions

Probenecid increases Cefuroxime levels in the blood.

Acid-reducing agents may lower Cefuroxime’s bioavailability and delay its absorption.

✔️ Contraindications

Known allergy to cephalosporins

History of Pseudomembranous Colitis

✔️ Precautions

Use cautiously in patients on diuretics or with a history of colitis.

✔️ Storage

Store in a cool, dry place below 30°C, away from light and moisture.

Keep out of reach of children.

Frequently Asked Questions (FAQ)

It is used to treat infections like pharyngitis, sinusitis, bronchitis, skin and soft tissue infections (SSTIs), UTIs, gonorrhoea, pneumonia, and typhoid fever.

Begins acting within 2–3 hours of ingestion.

The antibiotic remains effective for 4–8 hours.

No known interactions, but it's best to consult your doctor.

No, Cefaclav is not habit-forming.

Yes, it’s safe during breastfeeding, but monitor for allergic signs in infant

Yes, it can be used during pregnancy, preferably after medical advice.
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⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

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