Azithromycin
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Cinalid 500 is a broad-spectrum macrolide antibiotic used to treat a wide range of bacterial infections affecting the respiratory tract, skin, ears, eyes, and certain sexually transmitted infections. It is also effective in typhoid fever and community-acquired pneumonia.
Azithromycin binds to the 50S ribosomal subunit of bacteria, inhibiting protein synthesis by blocking transpeptidation. This action stops bacterial growth and replication.
🔹 Common:
Nausea
Vomiting
Diarrhea
Abdominal pain
🔹 Less Common:
Vaginitis
Dizziness
Headache
Flatulence
Rash
🔹 Rare/Potentially Serious:
Angioedema
Cholestatic jaundice
QT prolongation
Pseudomembranous colitis
✅ Adults:
Most infections: 500 mg once daily for 3 days
Chlamydia / Cervicitis / Urethritis / Chancroid: 1 g single dose
Gonorrhea: 2 g single dose
MAC prophylaxis: 1.2 g once weekly
MAC treatment: 500 mg daily with other antimicrobials
✅ Children:
Pharyngitis: 12 mg/kg/day for 5 days
Otitis media: 10 mg/kg/day × 1 day, then 5 mg/kg/day for 4 days
Pneumonia: 10 mg/kg × 1 day, then 5 mg/kg/day for 4 days
Max dose: 500 mg/day
✅ Administration:
Take 1 hour before or 2 hours after meals
Do not take with antacids (separate by 2 hours)
May increase levels of: digoxin, phenytoin, ciclosporin, terfenadine
Avoid antacids containing Mg/Al (reduce absorption)
Ergot derivatives: Risk of ergotism
Serious interaction with pimozide (risk of arrhythmia)
Keep in a dry place away from light and heat. Keep out of the reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.