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Levofloxacin Hemihydrate is indicated in Acute maxillary sinusitis, Acute bacterial exacerbation of chronic bronchitis, Nosocomial pneumonia Community-acquired pneumonia, Uncomplicated urinary tract infections Complicated urinary tract infections, Acute pyelonephritis, Uncomplicated & complicated skin and skin structure infections, Chronic bacterial prostatitis
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✅ Description:
- Acute maxillary sinusitis caused by Streptococcus pneumoniae, Haemophilus influenzae, or Moraxella catarrhalis.
- Acute bacterial exacerbation of chronic bronchitis caused by Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, or Moraxella catarrhalis.
- Community-acquired pneumonia caused by various bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella pneumoniae, Moraxella catarrhalis, Chlamydia pneumoniae, Legionella pneumophila, or Mycoplasma pneumoniae.
- Uncomplicated and complicated urinary tract infections caused by Escherichia coli, Klebsiella pneumoniae, or Staphylococcus saprophyticus.
- Acute pyelonephritis caused by Escherichia coli.
- Simple and complex skin and soft tissue infections caused by Staphylococcus aureus, Streptococcus pyogenes, Proteus mirabilis, or Enterococcus faecalis, including abscesses, cellulitis, boils, impetigo, pyoderma, and wound infections.
- Intestinal infection caused by Enterobacter, Escherichia coli, Campylobacter, Vibrio cholerae, Shigella, and Salmonella.
Safety Advices
Alcohol
CONSULT YOUR DOCTOR
Safe to consume alcohol with Orlev; does not cause harmful side effects.
Pregnancy
UNSAFE
Definite evidence of risk to the developing baby. Consult your doctor; may be prescribed in life-threatening situations
CONSULT YOUR DOCTOR
Limited human data suggests potential harm to the baby. Consult your doctor before using.
Driving:
UNSAFE
May decrease alertness, affect vision, and cause drowsiness and dizziness. Avoid driving if these symptoms occur.
Kidney
CONSULT YOUR DOCTOR
Use with caution in patients with kidney disease. Dose adjustment may be needed; consult your doctor.
Liver
CONSULT YOUR DOCTOR
Limited information on use in patients with liver disease. Consult your doctor; stop if signs of jaundice develop.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Uses of Orlev 500mg Tablet
Chronic bronchitis, acute bacterial sinusitis, anthrax, community-acquired pneumonia, skin and skin structure infections, nosocomial pneumonia, urinary tract infections, complicated skin and skin structure infections, acute pyelonephritis, chronic bacterial prostatitis.
✔️ How does Orlev 500mg Tablet
Antibiotics; stop the action of a bacterial enzyme called DNA-gyrase, preventing bacterial cell division and repair.
✔️ Side Effects of Orlev 500mg Tablet
- Common: Nausea, headache, diarrhea, insomnia, constipation, dizziness.
- Potentially Fatal: Anaphylaxis.
✔️ Quick Suggestions:
- Finish the full course even if symptoms improve.
- Discontinue and inform your doctor if you develop a rash, itchy skin, swelling, or have difficulty breathing.
- Diarrhea may occur but should stop when the course is complete.
- Notify your doctor if you feel pain in tendons, numbness, or tingling sensations.
- Inform your doctor if pregnant, planning to conceive, or breastfeeding.
✔️ Indication of Orlev 500mg Tablet
- Orlev is an antibiotic used to treat bacterial infections, including those of the urinary tract, nose, throat, skin, soft tissues, and lungs (pneumonia).
- Stops the further growth of causative microorganisms.
✔️ Pharmacology
Levofloxacin is a third-generation synthetic broad-spectrum fluoroquinolone antibiotic. It inhibits bacterial topoisomerase IV and DNA gyrase, essential for DNA replication, transcription, repair, and recombination. It demonstrates in vitro activity against a variety of gram-negative and gram-positive microorganisms.
✔️ Dosage & Administration of Orlev 500mg Tablet
- Tablets: 250 mg, 500 mg, or 750 mg orally every 24 hours, without regard to food.
- Oral Solution: Taken 1 hour before or 2 hours after eating.
- Injection: Administered by intravenous infusion. The dosage depends on the specific condition.
Dosage in Adults:
- Varies based on the type of infection, ranging from 500 mg once daily to 750 mg once daily for different durations.
Dosage in Children:
- Children 6 months to <5 years: 10 mg/kg every 12 hours.
- Children >5 years: 10 mg/kg every 24 hours.
How to take Orlev:
- Take as advised by your doctor.
- Swallow whole; do not chew, crush, or break.
- May be taken with or without food.
- Avoid Orlev with dairy products.
✔️ Interaction
- Additive effects on QT interval prolongation with certain medications.
- Reduced absorption with specific antacids and other medications.
- Altered glucose levels with antidiabetic agents.
- Increased risk of severe tendon disorders with corticosteroids.
- Increased risk of CNS stimulation and seizures with NSAIDs.
- Increased prothrombin time with warfarin.
✔️ Contraindications
Allergic history to levofloxacin, quinolone antibacterial drugs, or any component of the product.
✔️ Pregnancy & Lactation
Not recommended during pregnancy or breastfeeding due to unclear effects on the fetus or nursing baby.
✔️ Precautions & Warnings
- Levofloxacin injection should only be administered by slow intravenous drip.
- Adequate water intake during levofloxacin use.
- Dose adjustment in renal insufficiency.
- Avoid unnecessary exposure to sunlight or UV light.
- Not for use in children under 18 years.
✔️ Storage Conditions
Below 30°C, away from light & moisture. Keep out of reach of children.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
