Cyrin 10mg Tablet

✔️ Uses of Cyrin 10mg Tablet

• Muscle Spasm

✔️ How does Cyrin 10mg Tablet work?

Cyclobenzaprine is a muscle relaxant that acts on the central nervous system, specifically in the brain and spinal cord. It helps relieve muscle stiffness and spasms by affecting the communication between nerve cells. By doing so, it can improve pain and increase the range of motion in muscles.

✔️ Side Effects of Cyrin 10mg Tablet

• Nausea
• Dizziness
• Diarrhea
• Problems with eyesight
• Heart problems
• High blood pressure
• Breathlessness
• Bleeding from the stomach or bowel

✔️ Quick Suggestions:

• Use Cyrin 10mg Tablet as prescribed, along with rest and physical therapy.
• Take the medication with food to prevent stomach upset.
• Be cautious of potential side effects such as dizziness, and avoid activities that require concentration until you know how the medication affects you.
• Engage in physical activities like walking or swimming to strengthen muscles and relieve joint stiffness.
• Consider incorporating yoga for improved joint flexibility and pain management.
• Maintain a healthy weight through regular low-strain exercises and a balanced diet.
• Ensure adequate sleep to help reduce inflammation and swelling.
• Apply heat or cold therapy regularly using compresses on the affected joints.
• Practice stress-reducing activities such as meditation, reading, taking baths, or listening to soothing music.
• Explore additional therapies like acupuncture, massage, and physical therapy.
• Consume foods rich in antioxidants, such as berries, spinach, kidney beans, and dark chocolate.
• Include foods containing flavonoids, like soy, berries, broccoli, grapes, and green tea, as they can help reduce inflammation.
• Avoid smoking and alcohol consumption.
• Specifically, when taking Cyrin 10mg Tablet, avoid consuming alcohol as it can intensify drowsiness caused by the medication.

✔️ Indication

Cyrin 10mg Tablet is a medication used to treat muscle spasms (uncontrolled movements) due to muscle injury or sprain. The drug falls under muscle relaxants and is used to relax the muscle to prevent uncontrolled movements.

✔️ Pharmacology

Cyclobenzaprine, the active ingredient in Cyrin 10mg Tablet, is a centrally-acting skeletal muscle relaxant. It belongs to a class of drugs known as tricyclic antidepressants, although its primary use is for muscle relaxation rather than for its antidepressant properties. The structural similarity between cyclobenzaprine and tricyclic antidepressants allows them to share some pharmacological properties.

Cyclobenzaprine exerts its effects by acting on the brain stem, specifically targeting tonic-somatic motor activities. It influences both the alpha and gamma motor systems, which are responsible for muscle contraction and movement control. By reducing tonic motor activity, cyclobenzaprine helps alleviate muscle spasms and associated pain.

While cyclobenzaprine is primarily used as an adjunct in the symptomatic treatment of painful muscle spasms associated with musculoskeletal conditions, it's important to note that its mechanism of action and efficacy in this context is not fully understood. It is typically prescribed in combination with rest and physical therapy to provide relief from muscle spasms and improve symptoms.

✔️ Dosage & Administration of Cyrin 10mg Tablet

Adult Dosage:

• Initial dose: 5 mg taken three times a day (TID).
• If needed, the dose may be increased to 10 mg taken three times a day.
• The treatment duration should not exceed 2-3 weeks.
• The maximum dosage in a day is 60 mg.

Elderly Dosage:

• Initiate with a lower dose of 5 mg taken less frequently.
• The maximum dosage in a day is 60 mg.

Hepatic Impairment Dosage:

• Mild impairment: Start with a 5 mg dose taken less frequently.
• Moderate to severe impairment: Cyrin 10mg Tablet is not recommended for use in these cases.

Child Dosage:

• The safety and efficacy of Cyrin 10mg Tablet have not been established in children below 15 years of age.
• For children above 15 years of age: 5 mg taken every 8 hours (q8hr). The dose may be increased to 10 mg taken every 8 hours as needed.

Take Cyrin 10mg Tablet as advised by your doctor. Swallow the medicine as a whole and do not crush or chew the medicine. Your doctor will decide the right dose depending on your age, body weight, and disease condition.

✔️ Interaction

Medication interactions:

• Heart disease (digoxin): Cyrin 10mg Tablet may interact with digoxin, a medication used to treat heart conditions. It is important to consult with your doctor for appropriate monitoring and potential dosage adjustments when using these medications together.
• Painkillers (aspirin, morphine): There may be interactions between Cyrin 10mg tablet and painkillers such as aspirin or morphine. Your healthcare professional will evaluate the risks and benefits of concurrent use and may recommend appropriate adjustments in dosages or alternative medications.
• Blood thinner (clopidogrel): Concurrent use of Cyrin 10mg Tablet and clopidogrel, a blood thinner, may increase the risk of bleeding. Close monitoring and adjustment of medication dosages may be necessary under the guidance of your doctor.
• Antiparkinson's disease (selegiline): Cyrin 10mg Tablet may interact with selegiline, a medication used in the treatment of Parkinson's disease. Your doctor will monitor for potential interactions and adjust dosages if needed.
• Antidepressant (lithium): There may be interactions between Cyrin 10mg Tablet and lithium, an antidepressant. Close monitoring of lithium levels may be necessary when using these medications together.
• Blood pressure-lowering medicines (captopril): Cyrin 10mg Tablet may interact with captopril, a medication used to lower blood pressure. Your doctor will monitor your blood pressure and adjust medication dosages if required.
• Water pills/diuretics (amiloride): Concurrent use of Cyrin 10mg Tablet and amiloride, a diuretic, may require close monitoring of electrolyte levels and kidney function.
• Medicines for skin disease (tacrolimus): Cyrin 10mg Tablet may have interactions with tacrolimus, a medication used for certain skin conditions. Your doctor will monitor for any potential interactions and adjust dosages if necessary.
• Antiallergic (chlorpheniramine): Cyrin 10mg Tablet may interact with chlorpheniramine, an antiallergic medication. Your doctor will assess the risks and benefits of concurrent use and may recommend suitable alternatives or dosage adjustments.

Drug-Food interaction:

• Alcohol: It is advisable to avoid alcohol consumption while taking Cyrin 10mg Tablet as it may increase dizziness and the risk of stomach bleeding.

Drug-Disease interactions:

• Allergy, kidney disease, asthma, ulcer, and heart disease: Cyrin 10mg Tablet may have interactions with these specific diseases. It is important to inform your doctor about your medical history, including these conditions, as they will consider the risks and benefits of using the medication in your particular case and provide appropriate guidance.

✔️ Contraindications

If you have recently experienced a myocardial infarction (MI), have arrhythmias, or have severe liver disease, it is important to exercise caution and consult with your healthcare professional before taking any medication, including Cyrin 10mg Tablet. These conditions may affect the safety and suitability of using this medication. Your doctor will consider your specific medical history and assess the potential risks and benefits before recommending any treatment.

A recent myocardial infarction indicates a serious heart condition, and certain medications, including Cyrin 10mg Tablet, may carry risks for individuals with a history of cardiovascular events. It is essential to follow your doctor's guidance and recommendations regarding the use of medications in such cases.

Similarly, if you have arrhythmias (irregular heart rhythms) or severe liver disease, it can affect the metabolism and clearance of medications from your body. These conditions may require careful monitoring and dose adjustments to ensure the medication is safe and effective for you.

✔️ Pregnancy & Lactation

There have been no appropriate and well-controlled investigations on the teratogenic consequences of topically administered corticosteroids in pregnant women. As a result, only if the potential benefit outweighs the danger to the fetus should topical corticosteroids be administered during pregnancy. It's unclear if topical corticosteroid therapy would result in enough systemic absorption to produce measurable amounts in breast milk. Corticosteroids that are taken systemically are secreted in breast milk in amounts that are unlikely to harm the newborn. When topical corticosteroids are given to a nursing mother, however, caution should be maintained.

✔️ Precautions & Warnings

• Allergy: Do not take Cyrin 10mg Tablet if you are known to be allergic to it or any other medicines.
• Increased risk of heart attack or stroke: Cyrin 10mg Tablet may increase the risk of fatal heart attack or stroke. If you have recently undergone heart surgery, avoid using this medication.
• Pre-existing conditions: Inform your doctor if you have a thyroid disorder (hyperthyroidism), stomach ulcers, bleeding problems, clotting problems, or severe heart, liver, or kidney problems.
• Mood swings and depression: Contact your doctor immediately if you experience mood swings, depression, or have any suicidal thoughts while taking Cyrin 10mg Tablet.
• Liver function monitoring: Your doctor may advise regular blood tests to monitor your liver function while using Cyrin 10mg Tablet.
• Pre-existing disorders: Inform your doctor if you have or have had disorders of the stomach, blood circulation problems to the brain, asthma, porphyria, diabetes, or high blood pressure before taking Cyrin 10mg Tablet.
• Drowsiness and dizziness: Cyrin 10mg Tablet may cause drowsiness, sleepiness, fatigue, dizziness, and visual disturbance. It is important not to drive or operate machinery unless you are fully alert.
• Pregnancy and breastfeeding: Inform your doctor if you are pregnant or breastfeeding before starting Cyrin 10mg Tablet. They will evaluate the potential risks and benefits for you and your baby.
• Children: Cyrin 10mg Tablet should not be used in children below 18 years of age as its safety and efficacy have not been established for this age group.

✔️ Storage Conditions

• Store below 30°C in a cool and dry place
• Keep the medication away from moisture and direct sunlight
• Keep away from children and pets
• Do not flush the unused tablets or discard them in household waste
• Talk to your pharmacist about a safe way of discarding the unused or expired medications