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Generic Name: Naproxen 500mg
Manufacturer/Distributor: Square Pharmaceuticals Ltd.
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✅ Description:
Indications
Sonap 500 is a medication used to treat pain. In diseases such as osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout, and pediatric arthritis, it relieves pain and inflammation. Additionally, it aids in easing headaches, toothache, menstrual cramps, and pain in the muscles and joints.
Pharmacology
Naproxen is an anti-inflammatory, analgesic, and antipyretic non-steroidal anti-inflammatory drug (NSAID). It is quickly absorbed from the gastrointestinal tract and has a bioavailability of 95%.
Administration & Dosage
Naproxen Tablet-
- Rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis: The usual dose is 500-1000 mg daily in two divided doses after meals.
- Management of pain, primary dysmenorrhea, acute tendonitis & bursitis: Recommended starting dose is 500 mg followed by 500 mg every 12 hours or 250 mg every 6-8 hours. The initial total daily dose should not exceed 1250 mg and thereafter, the total daily dose should not exceed 1000 mg.
- Acute gout: Recommended starting dose is 750 mg followed by 250 mg every 8 hours until the attack has subsided.
Interaction
Expert inhibitors: lessen the antihypertensive impact of Expert inhibitors. Antacids & Sucralfate: delay the retention of Naproxen. Aspirin: increment antagonistic effects. Diuretics: decrease the natriuretic impact of Furosemide and Thiazides. Methotrexate: upgrade the harmfulness of Methotrexate. Warfarin: increment the chance of GI bleeding. Selective Serotonin Reuptake Inhibitors (SSRIs): increment the hazard of dying.
Contraindications
Patients who have a known hypersensitivity to naproxen should avoid taking it. Patients who have had asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs should not take it. In the setting of coronary artery bypass graft (CABG) surgery, it is contraindicated for the treatment of perioperative pain.
Side Effect
The following are the most commonly reported side effects:
Heartburn, abdominal pain, nausea, diarrhea, and dyspepsia are all symptoms of gastrointestinal problems.
Headache, vertigo, and drowsiness are symptoms of the Central Nervous System.
Pruritus (itching) and purpura are two dermatological conditions.
Edema and palpitation are symptoms of cardiovascular disease.
Other symptoms include visual and auditory disturbances.
Pregnancy & Lactation
Naproxen is classified as a pregnancy category C by the US Food and Drug Administration. So, unless the potential benefits to the other outweigh the potential risks to the fetus, Naproxen should be avoided during pregnancy and lactation.
Precautions & Warnings
Non-steroidal anti-inflammatory drugs, drugs for osteoarthritis, drugs for rheumatoid arthritis (NSAIDs)
Storage Conditions
Protect from light and moisture by storing below 30°C. Keep the medicine out of children's reach.
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