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Trevox D Sterile Solution 5ml Bottle
Dexamethasone 0.1% + Levofloxacin 0.5%
- Used for prevention and treatment of inflammation and infection following cataract surgery in adults.
- Always use under the supervision of a registered healthcare professional.
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✅ Description:
- Levofloxacin:
- Third-generation fluoroquinolone that inhibits bacterial DNA gyrase and topoisomerase IV, halting bacterial DNA replication.
- Targets DNA gyrase in Gram-negative and topoisomerase IV in Gram-positive bacteria.
- Dexamethasone:
- A glucocorticoid with strong anti-inflammatory, anti-allergic, and anti-exudative properties.
- Inhibits prostaglandin synthesis and neutrophil infiltration at the site of inflammation.
✔️ Each ml of sterile ophthalmic solution contains:
- Dexamethasone (as Sodium Phosphate): 1 mg
- Levofloxacin (as Hemihydrate): 5 mg
- Preservative: Benzalkonium Chloride 0.005%
✔️ Side Effects of Trevox D
- Common: Eye irritation, ocular hypertension, and headaches.
- Serious:
- Increased intraocular pressure (IOP) or glaucoma with prolonged use.
- Diabetics may risk subcapsular cataracts.
- Corneal thinning or perforation in rare cases.
✔️ Instructions for Use: Trevox D
- Wash hands thoroughly.
- Avoid contact between the bottle tip and the eye or skin.
- Tilt the head back, pull down the lower eyelid, and instill one drop into the pocket.
- After applying, press the inner corner of the eye to prevent systemic absorption.
✔️ Dosage of Trevox D
- Adults: One drop into the conjunctival sac every 6 hours for 7 days after surgery.
- Children: Not recommended for those under 18 years old due to insufficient safety data.
✔️ Overdose Effects
- Local overdose is unlikely to cause severe harm.
- Accidental oral ingestion is not expected to be life-threatening.
✔️ Interactions
Inform your doctor about all medications, including:
- Other eye drops or ointments.
- Ocular NSAIDs (e.g., ketorolac, diclofenac): Combined use with steroids can delay healing.
- Ritonavir or cobicistat (HIV treatment): May increase dexamethasone levels.
- Probenecid, cimetidine, cyclosporin: May alter levofloxacin absorption and metabolism.
✔️ Contraindications
- Hypersensitivity to any components.
- Viral diseases (e.g., herpes simplex keratitis, varicella).
- Mycobacterial or fungal infections of the eye.
✔️ Pregnancy & Lactation
- Pregnancy: Limited data; corticosteroids cross the placenta. Prolonged use may affect fetal development (e.g., low birth weight, vascular disorders).
- Lactation: Dexamethasone and levofloxacin may pass into breast milk; use with caution while nursing.
✔️ Precautions
- For ocular use only.
- Prolonged use may lead to antibiotic resistance or fungal overgrowth.
- Extended corticosteroid use can cause ocular hypertension or glaucoma but is unlikely within the recommended treatment period.
✔️ Storage Conditions
- Store below 30°C in a dry, dark place.
- Keep out of reach of children.
- Avoid contaminating the dropper tip.
- Do not use after 1 month of opening.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
