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A-B1 100mg Tablet 10pcs
A-B1 is primarily used to treat various manifestations of thiamine deficiency, including:
- Beriberi: A disease caused by thiamine deficiency, particularly common in alcoholics.
- Wernicke's Encephalopathy: A neurological disorder resulting from thiamine deficiency.
- Neuritis: Associated with pregnancy.
- Pellagra: Although primarily caused by niacin deficiency, thiamine can also play a role.
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✅ Description:
✔️ A-B1 may also be indicated prophylactically in conditions with:
Supplementation:
- Low dietary intake of thiamine.
- Impaired gastrointestinal absorption (e.g., due to alcohol consumption).
- Increased requirements (e.g., during pregnancy or a carbohydrate-rich diet).
Note: Follow your healthcare provider’s advice for usage.
✔️ Pharmacology
- Thiamine functions as a coenzyme (thiamine pyrophosphate) in the decarboxylation of α-ketoglutaric acid, essential for energy metabolism.
- Impacts the peripheral nervous system, gastrointestinal tract, and cardiovascular system. Symptoms include fatigue, anorexia, tachycardia, irritability, and neurological issues.
- Thiamine is well absorbed from the gastrointestinal tract, with a plasma half-life of approximately 24 hours. It is not stored in significant amounts in the body; excess is excreted in urine.
✔️ Dosage & Administration
- Prophylaxis: 3 to 10 mg daily.
- Mild Chronic Deficiency: 10 to 25 mg daily.
- Severe Deficiency: 200 to 300 mg daily.
Note: Always follow your healthcare provider’s advice for dosing.
✔️ Interactions
- Drug Interactions: No hazardous drug interactions were reported. Thiamine works synergistically with other B-complex vitamins, reducing adverse effects.
✔️ Contraindications
- No absolute contraindications, but the risk of anaphylaxis may increase with repeated parenteral administration.
- Avoid intravenous administration except in comatose patients; start a second course with a lower dose.
✔️ Side Effects
- Oral Administration: Generally safe with no adverse effects.
- Parenteral Administration: Potential for anaphylactic reactions, especially with high doses (400 mg) and repeated injections. Mild soreness may occur at the injection site.
✔️ Pregnancy & Lactation
- A-B1 can be safely administered to neonates, children, pregnant and lactating women, and elderly patients.
✔️ Storage Conditions
- Keep away from light and heat in a dry location. Keep out of children's reach.
Disclaimer:
ePharma sole intention is to ensure that its consumers get proper
information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
